Thermo Scientific™ HyperSep™ SPE Cartridges and Plates

Description

Thermo Scientific™ HyperSep™ solid phase extraction cartridges offer reproducible, reliable sample preparation in a traditional format. Available in a wide range of chemistries and bed weights, the cartridges are ideal for large samples and conform to industry standard configurations, allowing efficient routine processing by vacuum, by positive pressure or centrifugation.

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Reversed phase non-polar (hydrophobic) SPE cartridges & well plates
Extraction accomplished by non-polar, non-polar interactions and Van der Waals or dispersion force

HyperSep Retain PEP

Characteristics	Material	Typical applications
A versatile polymeric material for the retention of polar and non-polar analytes Surface area 550 to 750m2/g Particle size 40 to 60µm Pore size 55 to 90Å	Polystyrene divinylbenzene material surface modified with urea groups	Extraction of: Drugs and metabolites in biological matrices Environmental samples Desalting of peptides in serum, plasma, or biological fluids

HyperSep C18

Characteristics	Material	Typical applications
For non-polar to moderately polar compounds Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	Highly retentive alkyl-bonded silica phase	Extraction of: Drugs and their metabolites in biological matrices Trace organics in environmental water samples Toxins in food samples

HyperSep C8

Characteristics	Material	Typical applications
Less retentive alternative to C18 for non-polar to moderately polar compounds Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	A silica-based material used for hydrophobic compounds which tend to be retentive on C18 columns	Extraction of: Drugs and their metabolites in biological matrices Trace organics in environmental water samples Toxins in food samples

HyperSep Phenyl

Characteristics	Material	Typical applications
Alternative selectivity for retention of basic compounds Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	A silica-based material which offers alternative selectivity for aromatic compounds due to the presence of the benzene ring within the structure.	Extraction of: Benzodiazepines in biological matrices Aromatic compounds

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Mixed-mode—non-polar/ion exchange—SPE cartridges & well plates
Extraction accomplished using two functional groups: non-polar and ion exchange, which employs both hydrophobic and ionic retention. This phase is ideal for samples with complex structures.

HyperSep Retain-CX

Material	Characteristics	Typical applications
A versatile polymeric material for the enhanced retention of basic compounds Surface area 550 to 750m2/g Particle size 40 to 60µm Pore size 55 to 90Å	DVB material modified with sulfonic acid functional group for retention of basic	Analysis of a wide range of drugs of abuse including basic and neutral drugs from biological matrices.

HyperSep Retain-AX

Material	Characteristics	Typical applications
For retention of acidic compounds Surface area 550 to 750m2/g Particle size 40 to 60µm Pore size 55 to 90Å	A versatile polymeric material for the enhanced retention of acidic compounds.	Analysis of a range of acidic drugs of abuse from biological matrices, such as THC and its metabolites.

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Mixed-mode—normal phase/ion exchange—SPE cartridges & well plates
Phase accomplishes extraction using two functional groups: non-polar and ion exchange, which employs both hydrophobic and ionic retention. This mode deal for samples with complex structures

HyperSep Verify-CX

Material	Characteristics	Typical applications
Non-polar and anionic characteristics for improved analysis of basic drugs of abuse Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	A mixed-mode material based on two functional groups bonded to the silica base: a reversed phase C8 group and a strong cation exchanger.	Analysis of a range of basic drugs of abuse from biological matrices

HyperSep Verify-AX

Material	Characteristics	Typical applications
Non-polar and cationic characteristics for improved analysis of acidic drugs of abuse Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	Verify-AX is a mixed-mode material based on two functional groups bonded to the silica base: a reversed phase C8 group and a strong anion exchanger.	Analysis of a range of acidic drugs of abuse from biological matrices, including THC and its metabolites.

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Ion exchange SPE cartridges & well plates
Extraction accomplished by electrostatic interactions

HyperSep SAX

Material	Characteristics	Typical applications
For extraction of weak acids Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	Ideal for the extraction of negatively charged compounds from both aqueous and non-aqueous matrices, as well as the extraction of weak acids such as carboxylic acid.	Removal of acidic food pigments, removal of phenolic compounds, nucleic acids, and surfactants.

HyperSep SCX

Material	Characteristics	Typical applications
For extraction of charged basic compounds Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	Ideal for the extraction of positively charged compounds from both aqueous and non-aqueous matrices.	Extraction of: Antibiotics, drugs, organic bases, amino acids, catecholamines, and herbicides

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Normal phase SPE cartridges & well plates
Extraction accomplished by polar-polar interactions and dipole-dipole interactions

HyperSep Silica

Material	Characteristics	Typical applications
A polar sorbent primarily used to retain analytes from non-polar matrices Surface area 530m2/g Particle size 40 to 60µm Pore size 60Å	Silica material is primarily used to extract analytes from non-polar solvents such as hydrocarbons, less polar esters and ethers.	Extraction of: Aldehydes, amines, pesticides, herbicides, carotenoids, fat soluble vitamins, aflatoxins, fatty acids, and phospholipids

HyperSep Florisi

Material	Characteristics	Typical applications
Ideal for the isolation of polar compounds from non-polar matrices Surface area 289m2/g Particle size 40 to 60µm Pore size 60Å	Florisil is a magnesia-loaded silica gel	Extraction of: Pesticides using AOAC and EPA methods Polychlorinated biphenyls (PCBs) in transformer oil

HyperSep Cyano

Characteristics	Material	Typical applications
For retention of polar compounds from non-polar matrices Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	A silica-based material of low hydrophobicity. It is less retentive than either silica or diol.	Retention of polar compounds from hexane and oil

HyperSep Diol

Characteristics	Material	Typical applications
For extraction of polar compounds Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	A silica-based material	Normal phase extraction and purification of polar compounds

HyperSep Aminopropyl

Characteristics	Material	Typical applications
A polar sorbent for both polar and anion exchange interactions Surface area 470 to 530m2/g Particle size 40 to 60µm Pore size 60Å	A silica-based material which can be used as both a polar sorbent and a weak anion exchanger.	Extraction of Petroleum fractionation Saccharides Drugs and drug metabolites

HyperSep Hypercarb

Material	Characteristics	Typical applications
Unique material for retention of highly polar compounds 100% porous graphitic carbon material	Provides total pH stability retention and separation of highly polar species. Retention properties allow use of low bed weights	Ideal for problem analytes in SPE applications.