Description
Thermo Scientific™ Accucore™ columns are based on solid core (superficially porous) particles yielding highly efficient, rugged separations for high performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) applications. They offer lower backpressures than fully porous sub-2 µm particles. These are the columns of choice when sample volumes are limited, or when higher throughput is desired. We offer the widest portfolio of solid core chemistries (1.5, 2.6, 4 µm), which benefits you with options to optimize your resolution and separations.
| Selectivity | Functionality | Description |
| Reversed-phase hydrophobic interaction of nonpolar compounds (reversed-phase) | C30 | Designed for separating hydrophobic long chain, structurally related isomers |
| C18 | Excellent peak shape for hydrophobic interaction | |
| C8 | Similar selectivity to C18 but with less retention | |
| C4 | Short alkyl chain length, low hydrophobicity column for less retention than C18 or C8 | |
| RP/MS | Optimized for MS detection | |
| Reversed-phase with enhanced hydrolytic stability | aQ | Polar endcapped C18 are stable in 100% aqueous mobile phases and provide enhanced retention and resolution of polar analytes |
| Polar premium | Amide-embedded functional group | |
| Reversed-phase with selectivity for aromatic compounds | PFP: | Alternative selectivity in reverse phase applications. The fluorine atoms around the phenyl ring enhance pi-pi interactions with aromatic molecules, including hologenated compounds |
| pentafluoro- phenyl | ||
| Phenyl | Alternative selectivity in reverse phase applications, particularly for aromatic compounds | |
| Phenyl-Hexyl | Unique selectivity for aromatic and moderately polar analytes | |
| Biphenyl | Enhanced pi-pi interactions with aromatics, and separation of critical pairs and isomers | |
| Normal phase of non- polar and moderately polar organic compounds | Silica | Unbonded silica |
| HILIC; enhanced retention of polar and hydrophilic compounds | Urea-HILIC | Urea functional group |
| Amide-HILIC | Amide functional group |
