Corning® BioCoat™ Collagen IV-coated Flasks



Type IV Collagen is a ubiquitous component in basement membranes and provides the major structural support for this matrix. When the Collagen IV meshwork is assembled, it provides a scaffold for the assembly of other basement membrane components through interactions with laminin, entactin/nidogen, and heparan sulfate proteoglycan. Collagen IV is useful as a substrate for growth of epithelial, endothelial, muscle, and nerve cells. Collagen plays a role in the regulation of cell growth, differentiation and adhesion, as well as tissue formation.

Applications include:

  • Promotion of cell attachment and spreading
  • Cell differentiation and neurite outgrowth
  • Increased proliferation of PC12 cells
  • Studies of effects of collagen IV on cell behavior
  • Cell adhesion assays


  • Engelbreth-Holm-Swarm (EHS) lathrytic mouse tumor

Quality Control

  • Tested for ability to initiate differentiation (neurite outgrowth) of NG-108 rat glioma/mouse neuroblastoma cells
  • Tested and found negative for bacteria and fungi
  • Collagen IV purity >90% by SDS-PAGE


  • 2°C to 8°C. Do not freeze.

Cat. No. Product Name Qty./Pk Qty./Cs
354523 Corning® BioCoat™ Collagen IV 75cm² Rectangular Canted Neck Cell Culture Flask with Plug Seal Cap 5 / Pk 10 / Cs
354528 Corning® BioCoat™ Collagen IV 175cm² Rectangular Straight Neck Cell Culture Flask with Plug Seal Cap 5 / Pk 5 / Cs


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Corning® BioCoat™ Collagen IV-coated Flasks